ASA 125th Meeting Ottawa 1993 May

3aPA2. Acoustic radiation force and acoustical tweezers used in biomedical research.

Junru Wu

Dept. of Phys., Univ. of Vermont, Burlington, VT 05405

General analytical expressions for the acoustic radiation forces generated by focused and unfocused ultrasonic beams on a small compressible sphere [J. Wu and G. Du, J. Acoust. Soc. Am. 87, 997 (1990)] and a rigid cylinder [Wu et al., J. Acoust. Soc. Am. 87, 581 (1990)] are derived. A new tool for biomedical research, acoustic tweezers, is developed [J. Wu, J. Acoust. Soc. Am. 89, 2140 (1991)]. Several applications of acoustic radiation force at megahertz frequencies such as determination of the tensile strength of a single actin protein filament are discussed. [Work supported by NIH.]