Subject: Re: Estimating OHC/IHC Loss Proportion in Humans using DPOAEs From: Christine Rankovic <rankovic@xxxxxxxx> Date: Fri, 12 Apr 2013 11:20:07 -0400 List-Archive:<http://lists.mcgill.ca/scripts/wa.exe?LIST=AUDITORY>This is a multipart message in MIME format. ------=_NextPart_000_0004_01CE376F.B0685C50 Content-Type: text/plain; charset="us-ascii" Content-Transfer-Encoding: 7bit Jeff: I've used the OHC/IHC proportions provided by Moore and Glasburg (1997) to preprocess audiograms for articulation index calculations. These allow me to determine the amounts of the sensorineural hearing loss to model as attenuation or as noise, respectively. This usage may not have been their intention, although it works reasonably well with all the data I've examined. Moore and Glasburg derived their values from loudness functions (not DPOAEs). Lopez-Poveda and Johannessen (2012) arrived at very different values and dismiss the Moore and Glasburg work a little too easily, in my opinion. I don't necessarily agree that numbers from either study actually reflect hair cell count, but it is certainly an important area of study with direct and immediate application to hearing aids signal processing. Reference: Moore, BCJ and Glasberg, BR (1997). A model of loudness perception applied to cochlear hearing loss. Auditory Neuroscience 3: 289-311. Christine Rankovic, PhD From: AUDITORY - Research in Auditory Perception [mailto:AUDITORY@xxxxxxxx On Behalf Of Jeff Bruce Sent: Tuesday, April 09, 2013 3:00 PM To: AUDITORY@xxxxxxxx Subject: Estimating OHC/IHC Loss Proportion in Humans using DPOAEs Dear auditory list subscribers, I am searching for any publications which document the application of distortion product otoacoustic emissions (DPOAEs) as a way of estimating the proportion of outer/inner hair cell (OHC/IHC) loss in humans with hearing loss. I have performed several Google Scholar searches but can only seem to find methods applied to other animals. Alternatively, if you know of any other behavioural methods to estimate proportion of OHC/IHC loss, such as documented in the Journal of the Association for Research in Otolaryngology by Lopez-Poveda and Johannesen (2012), I would very much appreciate hearing about such techniques. Thank you. Note: the title of the paper I referred to is "Behavioral Estimates of the Contribution of Inner and Outer Hair Cell Dysfunction to Individualized Audiometric Loss" -- Jeff Bruce, Graduate Student/Teaching Assistant McMaster University, Psychology Building, PC320 Work: 905-525-9140 x24832 ------=_NextPart_000_0004_01CE376F.B0685C50 Content-Type: text/html; charset="us-ascii" Content-Transfer-Encoding: quoted-printable <html xmlns:v=3D"urn:schemas-microsoft-com:vml" = xmlns:o=3D"urn:schemas-microsoft-com:office:office" = xmlns:w=3D"urn:schemas-microsoft-com:office:word" = xmlns:m=3D"http://schemas.microsoft.com/office/2004/12/omml" = xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; = charset=3Dus-ascii"> <meta name=3DGenerator content=3D"Microsoft Word 12 (filtered medium)"> <style> <!-- /* Font Definitions */ @xxxxxxxx {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4;} @xxxxxxxx {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4;} @xxxxxxxx {font-family:Tahoma; panose-1:2 11 6 4 3 5 4 4 2 4;} /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {margin:0in; margin-bottom:.0001pt; font-size:12.0pt; font-family:"Times New Roman","serif";} a:link, span.MsoHyperlink {mso-style-priority:99; color:blue; text-decoration:underline;} a:visited, span.MsoHyperlinkFollowed {mso-style-priority:99; color:purple; text-decoration:underline;} span.EmailStyle17 {mso-style-type:personal-reply; font-family:"Calibri","sans-serif"; color:#1F497D;} .MsoChpDefault {mso-style-type:export-only;} @xxxxxxxx Section1 {size:8.5in 11.0in; margin:1.0in 1.0in 1.0in 1.0in;} div.Section1 {page:Section1;} --> </style> <!--[if gte mso 9]><xml> <o:shapedefaults v:ext=3D"edit" spidmax=3D"1026" /> </xml><![endif]--><!--[if gte mso 9]><xml> <o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"1" /> </o:shapelayout></xml><![endif]--> </head> <body lang=3DEN-US link=3Dblue vlink=3Dpurple> <div class=3DSection1> <p class=3DMsoNormal><span = style=3D'font-size:11.0pt;font-family:"Calibri","sans-serif"; color:#1F497D'>Jeff:<o:p></o:p></span></p> <p class=3DMsoNormal><span = style=3D'font-size:11.0pt;font-family:"Calibri","sans-serif"; color:#1F497D'><o:p> </o:p></span></p> <p class=3DMsoNormal><span = style=3D'font-size:11.0pt;font-family:"Calibri","sans-serif"; color:#1F497D'>I’ve used the OHC/IHC proportions provided by Moore = and Glasburg (1997) to preprocess audiograms for articulation index = calculations. These allow me to determine the amounts of the sensorineural hearing = loss to model as attenuation or as noise, respectively. This usage may not = have been their intention, although it works reasonably well with all the = data I’ve examined. Moore and Glasburg derived their values from loudness = functions (not DPOAEs). Lopez-Poveda and Johannessen (2012) arrived at very different values and dismiss the Moore and Glasburg work a little too = easily, in my opinion. I don’t necessarily agree that numbers from = either study actually reflect hair cell count, but it is certainly an important area = of study with direct and immediate application to hearing aids signal = processing.<o:p></o:p></span></p> <p class=3DMsoNormal><span = style=3D'font-size:11.0pt;font-family:"Calibri","sans-serif"; color:#1F497D'><o:p> </o:p></span></p> <p class=3DMsoNormal><span = style=3D'font-size:11.0pt;font-family:"Calibri","sans-serif"; color:#1F497D'>Reference: <o:p></o:p></span></p> <p class=3DMsoNormal><span = style=3D'font-size:11.0pt;font-family:"Calibri","sans-serif"; color:#1F497D'>Moore, BCJ and Glasberg, BR (1997). A model of = loudness perception applied to cochlear hearing loss. Auditory Neuroscience = 3: 289-311.<o:p></o:p></span></p> <p class=3DMsoNormal><span = style=3D'font-size:11.0pt;font-family:"Calibri","sans-serif"; color:#1F497D'><o:p> </o:p></span></p> <p class=3DMsoNormal><span = style=3D'font-size:11.0pt;font-family:"Calibri","sans-serif"; color:#1F497D'>Christine Rankovic, PhD<o:p></o:p></span></p> <p class=3DMsoNormal><span = style=3D'font-size:11.0pt;font-family:"Calibri","sans-serif"; color:#1F497D'><o:p> </o:p></span></p> <div style=3D'border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt = 0in 0in 0in'> <p class=3DMsoNormal><b><span = style=3D'font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span>= </b><span style=3D'font-size:10.0pt;font-family:"Tahoma","sans-serif"'> AUDITORY - = Research in Auditory Perception [mailto:AUDITORY@xxxxxxxx <b>On Behalf Of = </b>Jeff Bruce<br> <b>Sent:</b> Tuesday, April 09, 2013 3:00 PM<br> <b>To:</b> AUDITORY@xxxxxxxx<br> <b>Subject:</b> Estimating OHC/IHC Loss Proportion in Humans using = DPOAEs<o:p></o:p></span></p> </div> <p class=3DMsoNormal><o:p> </o:p></p> <div> <p class=3DMsoNormal>Dear auditory list subscribers,<br> <br> I am searching for any publications which document the application of distortion product otoacoustic emissions (DPOAEs) as a way of estimating = the proportion of outer/inner hair cell (OHC/IHC) loss in humans with = hearing loss. I have performed several Google Scholar searches but can only seem = to find methods applied to other animals.<o:p></o:p></p> <div> <p class=3DMsoNormal><o:p> </o:p></p> </div> <div> <p class=3DMsoNormal>Alternatively, if you know of any other behavioural = methods to estimate proportion of OHC/IHC loss, such as documented in the = Journal of the Association for Research in Otolaryngology by Lopez-Poveda and Johannesen (2012), I would very much appreciate hearing about such = techniques.<br> <br> Thank you.<o:p></o:p></p> </div> <div> <p class=3DMsoNormal><o:p> </o:p></p> </div> <div> <p class=3DMsoNormal>Note: the title of the paper I referred to is "Behavioral Estimates of the Contribution of Inner and Outer Hair = Cell Dysfunction to Individualized Audiometric Loss"<o:p></o:p></p> <div> <p class=3DMsoNormal><o:p> </o:p></p> </div> <p class=3DMsoNormal>-- <br> Jeff Bruce, Graduate Student/Teaching Assistant<br> McMaster University, Psychology Building, PC320<br> Work: 905-525-9140 x24832<o:p></o:p></p> </div> </div> </div> </body> </html> ------=_NextPart_000_0004_01CE376F.B0685C50--