Re: [AUDITORY] Sensitivity to ITDs with mismatched frequencies in each ear? ("Bernstein,Leslie" )


Subject: Re: [AUDITORY] Sensitivity to ITDs with mismatched frequencies in each ear?
From:    "Bernstein,Leslie"  <lbernstein@xxxxxxxx>
Date:    Thu, 25 Feb 2021 14:35:08 +0000

--_004_4fa7df2b78b647caaf8e805a29149799NSOITEXCMB21uchcnet_ Content-Type: multipart/alternative; boundary="_000_4fa7df2b78b647caaf8e805a29149799NSOITEXCMB21uchcnet_" --_000_4fa7df2b78b647caaf8e805a29149799NSOITEXCMB21uchcnet_ Content-Type: text/plain; charset="us-ascii" Content-Transfer-Encoding: quoted-printable Ah, but it all began 2-3 decades prior. I'm sticking up for the classic li= terature.? Les On 2/25/2021 12:30 AM, Chris Stecker wrote: *** Attention: This is an external email. Use caution responding, opening a= ttachments or clicking on links. *** Yes, it sure does seem like someone would have tested that by now. 1------------ Blanks DA, Buss E, Grose JH, Fitzpatrick DC, Hall JW 3rd. Interaural time d= iscrimination of envelopes carried on high-frequency tones as a function of= level and interaural carrier mismatch. Ear Hear. 2008;29(5):674-683. doi:1= 0.1097/AUD.0b013e3181775e03 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648125/<https://urldefense.co= m/v3/__https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648125/__;!!N0rdg9Wr!6= yxkCnWrCaePCLkLykzba1MIqsyWtZ5Xr3QVSH3FTAukXub6kdlIpEzJ5_lIoT-JlQ$> 2--------------- Goupell MJ, Stoelb C, Kan A, Litovsky RY. Effect of mismatched place-of-sti= mulation on the salience of binaural cues in conditions that simulate bilat= eral cochlear-implant listening. J Acoust Soc Am. 2013;133(4):2272-2287. do= i:10.1121/1.4792936 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631247/ 3-------------------- Kan A, Litovsky RY, Goupell MJ. Effects of interaural pitch matching and au= ditory image centering on binaural sensitivity in cochlear implant users. E= ar Hear. 2015;36(3):e62-e68. doi:10.1097/AUD.0000000000000135 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409917/ -Chris :-) On Feb 24, 2021, at 3:45 AM, Jan Schnupp <000000e042a1ec30-dmarc-request@xxxxxxxx= STS.MCGILL.CA><mailto:000000e042a1ec30-dmarc-request@xxxxxxxx> wrote= : Dear List, I am curious if you could recommend some reading for me. We have been incre= asingly interested in ITD coding with cochlear implants and have developed = a nice little animal model which shows a surprisingly robust behavioral ITD= sensitivity even if deafened in infancy and only implanted in young adulth= ood. One question we often get and which we would like to investigate is: how mu= ch does it matter if there is a bit of a mismatch between the frequency cha= nnels in the left and right ears? How badly do they have to be mismatched b= efore ITD sensitivity disappears? I kind of assumed that there must have been a lot of psychoacoustics on thi= s, at least in normally hearing human subjects. Of course at low frequencie= s, if you mismatch the left and right ears you get binaural beats, but what= about envelope ITDs? You could deliver for example trains of short gabor c= licks to each ear with a greater or lesser extent of carrier frequency mism= atch, and see how the mismatch affects ITD thresholds. It seems like such a= n obvious thing to try, surely somebody must have done this or something si= milar? But a quick look on google scholar didn't yield very much. A modelli= ng paper by Bonham and Lewis 1999 was the top hit. I haven't seen much in t= he way of data. Surely I must be missing something...? Any suggestions for = relevant reading gratefully accepted. Best wishes, Jan --------------------------------------- Prof Jan Schnupp City University of Hong Kong Dept. of Neuroscience 31 To Yuen Street, Kowloon Tong Hong Kong https://auditoryneuroscience.com<https://urldefense.com/v3/__https://audito= ryneuroscience.com/__;!!N0rdg9Wr!6yxkCnWrCaePCLkLykzba1MIqsyWtZ5Xr3QVSH3FTA= ukXub6kdlIpEzJ5_lDrSkPWQ$> http://jan.schnupp.net<https://urldefense.com/v3/__http://jan.schnupp.net/_= _;!!N0rdg9Wr!6yxkCnWrCaePCLkLykzba1MIqsyWtZ5Xr3QVSH3FTAukXub6kdlIpEzJ5_lofi= mGAQ$> -- Leslie R. Bernstein, Ph.D. | Professor Depts. of Neuroscience and Surgery (Otolaryngology) | UConn School of Medic= ine 263 Farmington Avenue, Farmington, CT 06030-3401 Office: 860.679.4622 | Fax: 860.679.2495 [cid:part4.FC474034.071D4ABA@xxxxxxxx --_000_4fa7df2b78b647caaf8e805a29149799NSOITEXCMB21uchcnet_ Content-Type: text/html; charset="us-ascii" Content-Transfer-Encoding: quoted-printable <html> <head> <meta http-equiv=3D"Content-Type" content=3D"text/html; charset=3Dus-ascii"= > </head> <body> <font face=3D"Verdana">Ah, but it all began 2-3 decades prior.&nbsp; I'm st= icking up for the classic literature.&#55357;&#56833;<br> <br> Les<br> </font><br> <div class=3D"moz-cite-prefix">On 2/25/2021 12:30 AM, Chris Stecker wrote:<= br> </div> <blockquote type=3D"cite" cite=3D"mid:1D1E233C-5B76-46D4-8C71-DD58374F61AE@xxxxxxxx= spatialhearing.org"> <div style=3D"background-color:#D5EAFF; padding:.8em; "> <div style=3D"font-size:12pt; color:#ff0000; text-align: center;=0A= font-family: 'Calibri',sans-serif;"> *** Attention: This is an external email. Use caution responding, opening a= ttachments or clicking on links. ***</div> </div> <div> <div class=3D"">Yes, it sure does seem like someone would have tested that = by now.&nbsp;</div> <div class=3D""><br class=3D""> </div> <div class=3D""><span style=3D"caret-color: rgb(48, 48, 48); color:=0A= rgb(48, 48, 48); font-family: arial, helvetica, clean,=0A= sans-serif; font-size: 13px; background-color: rgb(255, 255,=0A= 255);" class=3D"">1</span><font class=3D"" size=3D"2" face=3D"a= rial,=0A= helvetica, clean, sans-serif" color=3D"#303030"><span style=3D"= caret-color: rgb(48, 48, 48);" class=3D"">&#8212;&#8212;&#8212;&#8212;&#821= 2;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;</span></font></div> <div class=3D""><span style=3D"caret-color: rgb(48, 48, 48); color:=0A= rgb(48, 48, 48); font-family: arial, helvetica, clean,=0A= sans-serif; font-size: 13px; background-color: rgb(255, 255,=0A= 255);" class=3D"">Blanks DA, Buss E, Grose JH, Fitzpatrick DC, Hall JW 3rd. Interaural time discrimination of envelop= es carried on high-frequency tones as a function of level and interaural ca= rrier mismatch.&nbsp;</span><i style=3D"caret-color:=0A= rgb(48, 48, 48); color: rgb(48, 48, 48); font-family: arial,=0A= helvetica, clean, sans-serif; font-size: 13px;" class=3D"">Ear Hear</i><span style=3D"caret-color: rgb(48, 48, 48); color:=0A= rgb(48, 48, 48); font-family: arial, helvetica, clean,=0A= sans-serif; font-size: 13px; background-color: rgb(255, 255,=0A= 255);" class=3D"">. 2008;29(5):674-683. doi:10.1097/AUD.0b013e3= 181775e03</span></div> <div class=3D""><span style=3D"caret-color: rgb(48, 48, 48); color:=0A= rgb(48, 48, 48); font-family: arial, helvetica, clean,=0A= sans-serif; font-size: 13px; background-color: rgb(255, 255,=0A= 255);" class=3D""><br class=3D""> </span></div> <a href=3D"https://urldefense.com/v3/__https://www.ncbi.nlm.nih.gov/pmc/art= icles/PMC2648125/__;!!N0rdg9Wr!6yxkCnWrCaePCLkLykzba1MIqsyWtZ5Xr3QVSH3FTAuk= Xub6kdlIpEzJ5_lIoT-JlQ$" class=3D"" moz-do-not-send=3D"true">https://www.nc= bi.nlm.nih.gov/pmc/articles/PMC2648125/</a><br class=3D""> <div><br class=3D""> </div> <div><br class=3D""> </div> <div>2&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212= ;&#8212;&#8212;&#8212;&#8212;&#8212;</div> <div><br class=3D""> </div> <div><span style=3D"caret-color: rgb(48, 48, 48); color: rgb(48,=0A= 48, 48); font-family: arial, helvetica, clean, sans-serif;=0A= font-size: 13px; background-color: rgb(255, 255, 255);" class= =3D"">Goupell MJ, Stoelb C, Kan A, Litovsky RY. Effect of mismatched place-of-stimulation on the salience of binaural cues in con= ditions that simulate bilateral cochlear-implant listening.&nbsp;</span><i = style=3D"caret-color: rgb(48, 48, 48);=0A= color: rgb(48, 48, 48); font-family: arial, helvetica,=0A= clean, sans-serif; font-size: 13px;" class=3D"">J Acoust Soc Am</i><span style=3D"caret-color: rgb(48, 48, 48); color:=0A= rgb(48, 48, 48); font-family: arial, helvetica, clean,=0A= sans-serif; font-size: 13px; background-color: rgb(255, 255,=0A= 255);" class=3D"">. 2013;133(4):2272-2287. doi:10.1121/1.4792936</span></div> <div><span style=3D"caret-color: rgb(48, 48, 48); color: rgb(48,=0A= 48, 48); font-family: arial, helvetica, clean, sans-serif;=0A= font-size: 13px; background-color: rgb(255, 255, 255);" class= =3D""><br class=3D""> </span></div> <div><a class=3D"moz-txt-link-freetext" href=3D"https://www.ncbi.nlm.nih.go= v/pmc/articles/PMC3631247/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC36= 31247/</a></div> <div><br class=3D""> </div> <div><br class=3D""> </div> <div><br class=3D""> </div> <div>3&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212= ;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;</di= v> <div><br class=3D""> </div> <div><span style=3D"caret-color: rgb(48, 48, 48); color: rgb(48,=0A= 48, 48); font-family: arial, helvetica, clean, sans-serif;=0A= font-size: 13px; background-color: rgb(255, 255, 255);" class= =3D"">Kan A, Litovsky RY, Goupell MJ. Effects of interaural pitch matching and auditory image centering on binaural sensitivity in coc= hlear implant users.&nbsp;</span><i style=3D"caret-color: rgb(48, 48, 48); = color: rgb(48, 48, 48);=0A= font-family: arial, helvetica, clean, sans-serif; font-size:=0A= 13px;" class=3D"">Ear Hear</i><span style=3D"caret-color:=0A= rgb(48, 48, 48); color: rgb(48, 48, 48); font-family: arial,=0A= helvetica, clean, sans-serif; font-size: 13px;=0A= background-color: rgb(255, 255, 255);" class=3D"">. 2015;36(3):= e62-e68. doi:10.1097/AUD.0000000000000135</span></div> <div><span style=3D"caret-color: rgb(48, 48, 48); color: rgb(48,=0A= 48, 48); font-family: arial, helvetica, clean, sans-serif;=0A= font-size: 13px; background-color: rgb(255, 255, 255);" class= =3D""><br class=3D""> </span></div> <div><span style=3D"background-color: rgb(255, 255, 255);=0A= caret-color: rgb(48, 48, 48);" class=3D""><font class=3D"" size= =3D"2" face=3D"arial, helvetica, clean, sans-serif" color=3D"#303030"><a cl= ass=3D"moz-txt-link-freetext" href=3D"https://www.ncbi.nlm.nih.gov/pmc/arti= cles/PMC4409917/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409917/</a>= </font></span></div> <div><span style=3D"background-color: rgb(255, 255, 255);=0A= caret-color: rgb(48, 48, 48);" class=3D""><font class=3D"" size= =3D"2" face=3D"arial, helvetica, clean, sans-serif" color=3D"#303030"><br c= lass=3D""> </font></span></div> <div><span style=3D"background-color: rgb(255, 255, 255);=0A= caret-color: rgb(48, 48, 48);" class=3D""><font class=3D"" size= =3D"2" face=3D"arial, helvetica, clean, sans-serif" color=3D"#303030"><br c= lass=3D""> </font></span></div> <div><span style=3D"background-color: rgb(255, 255, 255);=0A= caret-color: rgb(48, 48, 48);" class=3D""><font class=3D"" size= =3D"2" face=3D"arial, helvetica, clean, sans-serif" color=3D"#303030">-Chri= s</font></span></div> <div><span style=3D"background-color: rgb(255, 255, 255);=0A= caret-color: rgb(48, 48, 48);" class=3D""><font class=3D"" size= =3D"2" face=3D"arial, helvetica, clean, sans-serif" color=3D"#303030"><br c= lass=3D""> </font></span></div> <div><span style=3D"background-color: rgb(255, 255, 255);=0A= caret-color: rgb(48, 48, 48);" class=3D""><font class=3D"" size= =3D"2" face=3D"arial, helvetica, clean, sans-serif" color=3D"#303030"><br c= lass=3D""> </font></span></div> <div>:-)</div> <div><br class=3D""> </div> <div><br class=3D""> </div> <div><br class=3D""> <blockquote type=3D"cite" class=3D""> <div class=3D"">On Feb 24, 2021, at 3:45 AM, Jan Schnupp <a class=3D"moz-tx= t-link-rfc2396E" href=3D"mailto:000000e042a1ec30-dmarc-request@xxxxxxxx= .CA"> &lt;000000e042a1ec30-dmarc-request@xxxxxxxx&gt;</a> wrote:</div> <br class=3D"Apple-interchange-newline"> <div class=3D""> <div dir=3D"ltr" class=3D"">Dear List, <div class=3D""><br class=3D""> </div> <div class=3D"">I am curious if you could recommend some reading for me. We= have been increasingly interested in ITD coding with cochlear implants and= have developed a nice little animal model which shows a surprisingly robus= t behavioral ITD sensitivity even if deafened in infancy and only implanted in young adulthood.&nbsp;</div> <div class=3D"">One question we often get and which we would like to invest= igate is: how much does it matter if there is a bit of a mismatch between t= he frequency channels in the left and right ears? How badly do they have to= be mismatched before ITD sensitivity disappears?</div> <div class=3D"">I kind of assumed that there must have been a lot of psycho= acoustics on this, at least in normally hearing human subjects. Of course a= t low frequencies, if you mismatch the left and right ears you get binaural= beats, but what about envelope ITDs?&nbsp;You could deliver for example trains of short gabor clicks to each ear with a = greater or lesser extent of carrier frequency mismatch, and see how the&nbs= p;mismatch affects ITD thresholds. It seems like such an obvious thing to t= ry, surely somebody must have done this or something similar? But a quick look on google scholar didn't yield very= much. A modelling paper by Bonham and Lewis 1999 was the top hit. I haven'= t seen much in the way of data. Surely I must be missing something...? Any = suggestions for relevant reading gratefully&nbsp;accepted.&nbsp;</div> <div class=3D""><br class=3D""> </div> <div class=3D"">Best wishes,</div> <div class=3D""><br class=3D""> </div> <div class=3D"">Jan</div> <div class=3D""><br class=3D"" clear=3D"all"> <div class=3D""> <div dir=3D"ltr" class=3D"gmail_signature" data-smartmail=3D"gmail_signatur= e"> <div dir=3D"ltr" class=3D""> <div class=3D""> <div dir=3D"ltr" class=3D""> <div class=3D""> <div dir=3D"ltr" class=3D""> <div dir=3D"ltr" class=3D""> <div dir=3D"ltr" class=3D""> <div dir=3D"ltr" class=3D""> <div style=3D"font-size:12.8px" class=3D""><br class=3D""> </div> <div style=3D"font-size:12.8px" class=3D"">--------------------------------= -------</div> <div style=3D"font-size:12.8px" class=3D"">Prof Jan Schnupp<br class=3D""> City University of Hong Kong<br class=3D""> Dept. of Neuroscience</div> <div class=3D""> <div style=3D"font-size:12.8px" class=3D"">31 To Yuen Street,&nbsp;</div> <div style=3D"font-size:12.8px" class=3D""><span style=3D"font-size:12.8px"= class=3D"">Kowloon Tong</span></div> <div style=3D"font-size:12.8px" class=3D"">Hong Kong</div> <div style=3D"font-size:12.8px" class=3D""><br class=3D""> </div> <a href=3D"https://urldefense.com/v3/__https://auditoryneuroscience.com/__;= !!N0rdg9Wr!6yxkCnWrCaePCLkLykzba1MIqsyWtZ5Xr3QVSH3FTAukXub6kdlIpEzJ5_lDrSkP= WQ$" target=3D"_blank" class=3D"" moz-do-not-send=3D"true">https://auditory= neuroscience.com</a></div> <div class=3D""><a href=3D"https://urldefense.com/v3/__http://jan.schnupp.n= et/__;!!N0rdg9Wr!6yxkCnWrCaePCLkLykzba1MIqsyWtZ5Xr3QVSH3FTAukXub6kdlIpEzJ5_= lofimGAQ$" target=3D"_blank" class=3D"" moz-do-not-send=3D"true">http://jan= .schnupp.net</a></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </blockquote> </div> <br class=3D""> </div> </blockquote> <br> <br> <div class=3D"moz-signature">-- <br> <!-- saved from url=3D(0048)data:text/html;filename=3DUCHSig.html;base64,Cj= whLS0gc2F2ZWQgZnJvbSB1cmw9KDAwNDgpZmlsZTovLy9EOi9Vc2Vycy9sYmVybnN0ZWluL1BpY= 3R1cmVzL1VDSFNpZy5odG1sIC0tPgo8aHRtbD48aGVhZD48bWV0YSBodHRwLWVxdWl2PSJDb250= ZW50LVR5cGUiIGNvbnRlbnQ9InRleHQvaHRtbDsgY2hhcnNldD1VVEYtOCI+CgogICAgCiAgICA= 8dGl0bGU+PC90aXRsZT4KICA8L2hlYWQ+CiAgPGJvZHkgYmdjb2xvcj0iI0ZGRkZGRiIgdGV4dD= 0iIzAwMDAwMCI+CiAgICA8Yj48c3BhbiBzdHlsZT0iZm9udC1zaXplOjEwLjBwdDtmb250LWZhb= WlseTomcXVvdDtBcmlhbCZxdW90OyxzYW5zLXNlcmlmOwogICAgICAgIG1zby1mYXJlYXN0LWZv= bnQtZmFtaWx5OiZxdW90O1RpbWVzIE5ldyBSb21hbgogICAgICAgIFw7Y29sb3JcOlwjMDAyMDQ= 4JnF1b3Q7Ij5MZXNsaWUgUi4gQmVybnN0ZWluLCBQaC5ELiA8L3NwYW4+PC9iPjxiPjxzcGFuIH= N0eWxlPSJmb250LXNpemU6MTAuMHB0O2ZvbnQtZmFtaWx5OiZxdW90O0FyaWFsJnF1b3Q7LHNhb= nMtc2VyaWY7CgogICAgICAgIG1zby1mYXJlYXN0LWZvbnQtZmFtaWx5OiZxdW90O1RpbWVzIE5l= dyBSb21hbgogICAgICAgIFw7Y29sb3JcOlwjNTg1ODU4JnF1b3Q7Ij58IDwvc3Bhbj48L2I+PHN= wYW4gc3R5bGU9ImZvbnQtc2l6ZToxMC4wcHQ7Zm9udC1mYW1pbHk6JnF1b3Q7QXJpYWwmcXVvdD= ssc2Fucy1zZXJpZjttc28tZmFyZWFzdC1mb250LWZhbWlseToKJnF1b3Q7VGltZXMKCiAgICAgI= E5ldyBSb21hbiBcO2NvbG9yXDpcIzU4NTg1OCZxdW90OyI+UHJvZmVzc29yPC9zcGFuPjxzcGFu= IHN0eWxlPSJtc28tZmFyZWFzdC1mb250LWZhbWlseTogJnF1b3Q7VGltZXMgTmV3IFJvbWFuJnF= 1b3Q7Ij48bzpwPjwvbzpwPjwvc3Bhbj48c3BhbiBzdHlsZT0iZm9udC1zaXplOjEwLjBwdDtmb2= 50LWZhbWlseTomcXVvdDtBcmlhbCZxdW90OyxzYW5zLXNlcmlmOwogICAgICBtc28tZmFyZWFzd= C1mb250LWZhbWlseTomcXVvdDtUaW1lcyBOZXcgUm9tYW4KICAgICAgXDtjb2xvclw6XCM1ODU4= NTgmcXVvdDsiPjxicj4KICAgICAgRGVwdHMuIG9mIE5ldXJvc2NpZW5jZSBhbmQgU3VyZ2VyeSA= oT3RvbGFyeW5nb2xvZ3kpIHwgVUNvbm4gU2Nob29sCiAgICAgIG9mIE1lZGljaW5lIDwvc3Bhbj= 48YnI+CiAgICA8c3BhbiBzdHlsZT0iZm9udC1zaXplOjEwLjBwdDtmb250LWZhbWlseTomcXVvd= DtBcmlhbCZxdW90OyxzYW5zLXNlcmlmOwogICAgICBtc28tZmFyZWFzdC1mb250LWZhbWlseTom= cXVvdDtUaW1lcyBOZXcgUm9tYW4KICAgICAgXDtjb2xvclw6XCM1ODU4NTgmcXVvdDsiPjwvc3B= hbj48c3BhbiBzdHlsZT0iZm9udC1zaXplOjEwLjBwdDtmb250LWZhbWlseTomcXVvdDtBcmlhbC= ZxdW90OyxzYW5zLXNlcmlmOwogICAgICBtc28tZmFyZWFzdC1mb250LWZhbWlseTomcXVvdDtUa= W1lcyBOZXcgUm9tYW4KICAgICAgXDtjb2xvclw6XCM1ODU4NTgmcXVvdDsiPjI2MyBGYXJtaW5n= dG9uIEF2ZW51ZSwgRmFybWluZ3RvbiwgQ1QKICAgICAgMDYwMzAtMzQwMTwvc3Bhbj48YnI+CiA= gICA8c3BhbiBzdHlsZT0iZm9udC1zaXplOjEwLjBwdDtmb250LWZhbWlseTomcXVvdDtBcmlhbC= ZxdW90OyxzYW5zLXNlcmlmOwogICAgICBtc28tZmFyZWFzdC1mb250LWZhbWlseTomcXVvdDtUa= W1lcyBOZXcgUm9tYW4KICAgICAgXDtjb2xvclw6XCM1ODU4NTgmcXVvdDsiPjwvc3Bhbj48c3Bh= biBzdHlsZT0iZm9udC1zaXplOjEwLjBwdDtmb250LWZhbWlseTomcXVvdDtBcmlhbCZxdW90Oyx= zYW5zLXNlcmlmOwogICAgICBtc28tZmFyZWFzdC1mb250LWZhbWlseTomcXVvdDtUaW1lcyBOZX= cgUm9tYW4KICAgICAgXDtjb2xvclw6XCM1ODU4NTgmcXVvdDsiPk9mZmljZTogODYwLjY3OS40N= jIyIHwgRmF4OiA4NjAuNjc5LjI0OTU8YnI+CiAgICAgIDxicj4KICAgICAgPGltZyBhbHQ9IiIg= c3JjPSJmaWxlOi8vL0Q6L1VzZXJzL2xiZXJuc3RlaW4vUGljdHVyZXMvdWNvbm5oZWFsdGhfc3R= hY2tlZF9ibHVlX2VtYWlsLnBuZyIgaGVpZ2h0PSI0OCIgd2lkdGg9IjEyNSI+PGJyPgogICAgPC= 9zcGFuPgogIAoKPC9ib2R5PjwvaHRtbD4=3D --> <title></title> <b><span style=3D"font-size:10.0pt;font-family:&quot;Arial&quot;,sans-serif= ;=0A= mso-fareast-font-family:&quot;Times New Roman=0A= \;color\:\#002048&quot;">Leslie R. Bernstein, Ph.D. </span></b><b><span style=3D"font-size:10.0pt;font-family:&quot;Arial&quot;= ,sans-serif;=0A= mso-fareast-font-family:&quot;Times New Roman=0A= \;color\:\#585858&quot;">| </span></b><span style=3D"font-size:10.0pt;font-family:&quot;Arial&quot;,sa= ns-serif;mso-fareast-font-family:&quot;Times=0A= New Roman \;color\:\#585858&quot;">Professor</span><span style=3D"m= so-fareast-font-family: &quot;Times New Roman&quot;"><o:p></o:p></span><spa= n style=3D"font-size:10.0pt;font-family:&quot;Arial&quot;,sans-serif;=0A= mso-fareast-font-family:&quot;Times New Roman=0A= \;color\:\#585858&quot;"><br> Depts. of Neuroscience and Surgery (Otolaryngology) | UConn School of Medic= ine </span> <br> <span style=3D"font-size:10.0pt;font-family:&quot;Arial&quot;,sans-serif;= =0A= mso-fareast-font-family:&quot;Times New Roman=0A= \;color\:\#585858&quot;"></span><span style=3D"font-size:10.0pt;fon= t-family:&quot;Arial&quot;,sans-serif;=0A= mso-fareast-font-family:&quot;Times New Roman=0A= \;color\:\#585858&quot;">263 Farmington Avenue, Farmington, CT 06030-3401</span><br> <span style=3D"font-size:10.0pt;font-family:&quot;Arial&quot;,sans-serif;= =0A= mso-fareast-font-family:&quot;Times New Roman=0A= \;color\:\#585858&quot;"></span><span style=3D"font-size:10.0pt;fon= t-family:&quot;Arial&quot;,sans-serif;=0A= mso-fareast-font-family:&quot;Times New Roman=0A= \;color\:\#585858&quot;">Office: 860.679.4622 | Fax: 860.679.2495<br> <br> <img alt=3D"" src=3D"cid:part4.FC474034.071D4ABA@xxxxxxxx" width=3D"125" he= ight=3D"48"><br> </span></div> </body> </html> --_000_4fa7df2b78b647caaf8e805a29149799NSOITEXCMB21uchcnet_-- --_004_4fa7df2b78b647caaf8e805a29149799NSOITEXCMB21uchcnet_ Content-Type: image/png; name="uconnhealth_stacked_blue_email.png" Content-Description: uconnhealth_stacked_blue_email.png Content-Disposition: inline; filename="uconnhealth_stacked_blue_email.png"; size=796; creation-date="Thu, 25 Feb 2021 14:35:08 GMT"; modification-date="Thu, 25 Feb 2021 14:35:08 GMT" Content-ID: <part4.FC474034.071D4ABA@xxxxxxxx> Content-Transfer-Encoding: base64 iVBORw0KGgoAAAANSUhEUgAAAH0AAAAwCAMAAAALmIWlAAAAGXRFWHRTb2Z0d2FyZQBBZG9iZSBJ bWFnZVJlYWR5ccllPAAAADNQTFRFKzVYHCZM4eLn8PHzpKi30dTbaG+IlZqrs7fDWWB8O0Nkd32U wsXPSlJwhoufDRhA////A68jmAAAABF0Uk5T/////////////////////wAlrZliAAACYklEQVR4 2uzY22KDIAwAUC7e6gjw/187gUC4OetaupflaTXKWSuBKNMuJptC+QMCP20auPHBQCubBWU46K24 uB7NfZ58ZqaMP8D8AEBHtT/goXnB8WPwBf8r1WYUXWxUOZobHcJXIMcfONclmE4s0lrRzYBIOjvT jX5WV6YbP2ZQJ6TWjfiAbuYzHW7p+xpuolQrP83sjQ5nupnu6LqaJ92MbnSznulcfkBHpNXNY6y+ c0JKnWX1eFeflQt5qcNESKnrQMrf6LSAXeiWkEoXdOU4nZBKxzPnoTohtW5ZZyK8W09Io6tYjyP1 iDS6XbAeh815S0irS6zHUfXuB0Ok1S3W41AdEWh1/Nb7UD1bWytd0LY4ThdnerYbBJ1taT5XBmy4 J8mNnWagp5fbba6HeiTdneK6vNgoFj0EhyO4eSZT6AlpdNXoNzqYi94GbIU0eqhHp3d5drRf4heZ Uo9Iq8vYptup6VB37H6m/W6m0hFpdaxH3/yK9cHpVq5Zy59n2GMV/QxPGdV9NElPE9njyOozsfWW Kq6j7bLuw97KPBnM/mX86//6n+tH/yLKP7AUXcyd80Lx53WnspB47ty5qKND1gLockfIFzHR7srp Q7X0+6GgHPNFXedPyaN1CPFli71z+ZBeTxbcI2RXxwOQj/lW/Ui610Z6gA4a32WRrssXYbO76V/Z y6FLnZVj/qCnqGcdZE1DeFKcntWrMV/RZXCh7B/fpF/+8tQQx6J74y9/Oeuyrm75+Jyf8oKWH9CL 1SYNJtJ91HTOAD2fdjPN9UcsumwmDNYXqvPtOLa9pH8LMACnoV0siZAyOAAAAABJRU5ErkJggg== --_004_4fa7df2b78b647caaf8e805a29149799NSOITEXCMB21uchcnet_--


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