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Hair Cell Models

The paper by Glowatzki and Fuchs ('Transmitter release at the hair
cell ribbon synapse' in Nature neuroscience, v 5 nr 2, Feb 2002)
appears to do a good job of forcing a rethink of the available hair
cell models. They show that the ribbon synapse seems to operate by
multivesicle release, with the number of vesicles being released in a
single event insensitive to degree of depolarization. They do note
that the amplitude histogram should be described by binomial
statistics; however, they were unable to fit binomial distributions
to this data.

This raises the following question: Consider the curve relating the
rate of vesicle release events at a hair cell ribbon synapse to
depolarization. Is there any evidence that the spontaneous rate of
vesicle release events lies on the same curve?
Harry Erwin, PhD, Senior Lecturer of Computing, University of
Sunderland. Computational neuroscientist modeling bat bioacoustics
and behavior. <http://www.cet.sunderland.ac.uk/~cs0her/index.html>