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Re: Estimating OHC/IHC Loss Proportion in Humans using DPOAEs



I’ve used the OHC/IHC proportions provided by Moore and Glasburg (1997) to preprocess audiograms for articulation index calculations.  These allow me to determine the amounts of the sensorineural hearing loss to model as attenuation or as noise, respectively.  This usage may not have been their intention, although it works reasonably well with all the data I’ve examined.  Moore and Glasburg derived their values from loudness functions (not DPOAEs).  Lopez-Poveda and Johannessen (2012) arrived at very different values and dismiss the Moore and Glasburg work a little too easily, in my opinion.  I don’t necessarily agree that numbers from either study actually reflect hair cell count, but it is certainly an important area of study with direct and immediate application to hearing aids signal processing.



Moore, BCJ and Glasberg, BR (1997).  A model of loudness perception applied to cochlear hearing loss.  Auditory Neuroscience 3: 289-311.


Christine Rankovic, PhD


From: AUDITORY - Research in Auditory Perception [mailto:AUDITORY@xxxxxxxxxxxxxxx] On Behalf Of Jeff Bruce
Sent: Tuesday, April 09, 2013 3:00 PM
To: AUDITORY@xxxxxxxxxxxxxxx
Subject: Estimating OHC/IHC Loss Proportion in Humans using DPOAEs


Dear auditory list subscribers,

I am searching for any publications which document the application of distortion product otoacoustic emissions (DPOAEs) as a way of estimating the proportion of outer/inner hair cell (OHC/IHC) loss in humans with hearing loss.  I have performed several Google Scholar searches but can only seem to find methods applied to other animals.


Alternatively, if you know of any other behavioural methods to estimate proportion of OHC/IHC loss, such as documented in the Journal of the Association for Research in Otolaryngology by Lopez-Poveda and Johannesen (2012), I would very much appreciate hearing about such techniques.

Thank you.


Note: the title of the paper I referred to is "Behavioral Estimates of the Contribution of Inner and Outer Hair Cell Dysfunction to Individualized Audiometric Loss"


Jeff Bruce, Graduate Student/Teaching Assistant
McMaster University, Psychology Building, PC320
Work: 905-525-9140 x24832