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The Apostolides lab at University of Michigan’s Kresge Hearing Research Center opens Fall 2018. https://www.apostolideslab.org We are looking for creative and motivated post-docs who want to understand the synaptic and cellular bases of auditory perception. Our primary techniques are patch-clamp electrophysiology and 2-photon imaging in brain slices and in behaving mice. Key questions we want to answer are: -How do neural circuits extract meaningful information from noisy or ambiguous sensory signals? -How do “higher order”, associational brain regions control the encoding of behaviorally relevant auditory information in “primary” sensory regions? -To what extent do neuromodulators such as serotonin, noradrenaline and acetylcholine control specific cell-types in central auditory circuits, and what are the consequences for central auditory function? -What are the cellular mechanisms governing synaptic plasticity in animal models of hearing disorders?
Qualifications: You should have (or be close to completing) a Ph.D. and/or M.D., a passion for scientific discovery, and experience with patch-clamp electrophysiology, 2-photon imaging, animal behavior, and/or acoustics/auditory psychophysics. A detail-oriented, quantitative mindset and experience with scientific programming is critical. Please send an email with your CV, a few sentences stating your career goals, and contact info for 3 references directly to Pierre Apostolides (piaposto@xxxxxxxxxxxxx) ********************************************************** |