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Re: Individual Differences in Outer Hair Cell Function
Good luck with your search. One thing though: since you are talking
about cross-species, don't forget about musicians who, I should know,
represent a species on their own.
At 09:36 AM 3/17/2007, James D. Miller wrote:
Does anyone know of published evidence that people with normal
densities (#OHC/mm) of normal outer hairs (they look normal, have
all their stereo cilia and mitochondria etc), differ in function?
That is, do some with normal outer hair cells have better cochlear
amplifiers with sharper tuning than others with the same densities
(#OHC/mm) of completely normal outer hair cells? I would be even
interested in cross-species comparisons, if they make sense, since
so much of what we know about hearing is, in fact, based on
I ask because a reviewer of a recent grant proposal of mine
appeared to think that everybody should know that some people have
better outer hair cells than others, even when the OHC density per
unit length is the same and when there is no sign of injury or
deficit. I suppose it's a possiblity, but is there any evidence of any kind?
James D. Miller, Ph.D.
Communication Disorders Technology, Inc.
Indiana University Research Park
501 N. Morton Street Suite 215
Bloomington, IN 47404
Business Phone: (812)336-1766
Cingular Cell Phone: (812)360-0612